This project will result in a better understanding of the factors that contribute to the long-term prevention of adolescent depression, including individual and family factors that influence intervention use and response. Expanding a National Institutes of Health-funded project, funding from the Virginia B. Toulmin Foundation provides for the collection of new data on parental mental health and the effects of parental illness on youth depression and CATCH-IT intervention use. Gladstone expects to learn more about the factors that influence whether or not parents will use the parent intervention, whether they will benefit from it, and whether it will alter their parenting behaviors. Moreover, this project will tell researchers more about the effects of parental illness on teens’ response to a depression prevention resource (i.e., when parents are depressed, are teens less willing to use CATCH-IT) and whether the course of parental mental health concerns is relevant to teens’ intervention responses. The ultimate goal of this project is to use the data collected about the effects of parental illness on teen intervention use and response to inform the timing of preventive efforts for teens, and to suggest strategies for addressing parental illness at the same time as promoting mental health efforts for at-risk youth