The science of medicine has demonstrated unprecedented success during the past several decades, yet the humane aspect of medical practice has become less integral to the culture of clinical medicine. At issue is the conviction that clinicians have become excessively impersonal in caring for patients, resulting in a backlash of patient frustration and alienation. Given the vast degree of structural reorganization now in progress, including the influx of females into this once male-dominated profession, this paper examines gender differences in professional practice philosophy and medical decision-making as part of a larger study.