This paper reviews research regarding high-skilled migration. The authors adopt a data-driven perspective, bringing together and describing several ongoing research streams that range from the construction of global migration databases to the legal codification of national policies regarding high-skilled migration, to the analysis of patent data regarding cross-border inventor movements. A common theme throughout this research is the importance of agglomeration economies for explaining high-skilled migration. The authors highlight some key recent findings and outline the major gaps that they hope will be tackled in the future.